Pyridone 6, CAS [[457081-03-7]]

Artikelnummer: FBM-10-5555
Artikelname: Pyridone 6, CAS [[457081-03-7]]
Artikelnummer: FBM-10-5555
Hersteller Artikelnummer: 10-5555
Alternativnummer: FBM-10-5555-1MG,FBM-10-5555-5MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: JAK Inhibitor I
pan-JAK inhibitor
Molekulargewicht: 309.34
Reinheit: 98% by HPLC NMR (Conforms)
Formulierung: Off-white solid
CAS Nummer: [457081-03-7]
Formel: C18H16FN3O
Anwendungsbeschreibung: Potent, ATP-competitive pan-JAK inhibitor. Inhibits 1, 2 and 3 (IC50=1, 5 and 15 nM respectively) as well as JAK family member Tyk2 (IC50=1 nM).1 Also tested against 21 other kinases with inhibition ranging from 130 nm to >10 mM. Inhibits IL2 and IL4-dep