Rat SFRP1 protein, His tag (active), Unconjugated

Artikelnummer: GTX00065-PRO
Artikelname: Rat SFRP1 protein, His tag (active), Unconjugated
Artikelnummer: GTX00065-PRO
Hersteller Artikelnummer: GTX00065-pro
Alternativnummer: GTX00065-PRO-10
Hersteller: GeneTex
Kategorie: Proteine/Peptide
Applikation: FA
Spezies Reaktivität: Rat
Konjugation: Unconjugated
Alternative Synonym: secreted frizzled-related protein 1 , sFRP-1
a secreted protein involved in binding Wnt and antagonizing Wnt signaling [RGD, Feb 2006]
NCBI: 84402
UniProt: Q9R168
Puffer: Reconstitute with 20mM Tris (pH8.0) and 150mM NaCl (pH8.0) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris (pH8.0), 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System: E. coli
Formulierung: Lyophilized powder
Sequenz: N-terminal His-Tag, Val8~Asp153
Anwendungsbeschreibung: Secreted frizzled-related protein 1, also known as SFRP1 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. It acts as a biphasic modulator of Wnt signaling, counteracting
GTX00065-pro Image
WB analysis of GTX00065-pro Rat SFRP1 protein (active).
Functional ELISA analysis of GTX00065-pro Rat SFRP1 protein (active) which can bind immobilized WNT2 protein.
Cell suppression effect of GTX00065-pro Rat SFRP1 protein (active). Cell viability was measured by Cell Counting Kit-8 (CCK-8).
(A) Unstimulated HepG2 cells cultured in DMEM for 96hrs.
(B) HepG2 cells cultured in DMEM, stimulated with 1000 ng/ml SFRP1 for 96hrs.