Human IL12A + IL27B fusion protein, His tag (active), Unconjugated

Artikelnummer: GTX00070-PRO
Artikelname: Human IL12A + IL27B fusion protein, His tag (active), Unconjugated
Artikelnummer: GTX00070-PRO
Hersteller Artikelnummer: GTX00070-pro
Alternativnummer: GTX00070-PRO-10
Hersteller: GeneTex
Kategorie: Proteine/Peptide
Applikation: FA
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: interleukin 12A , Epstein-Barr virus induced 3 , CLMF , IL-12A , NFSK , NKSF1 , P35 , IL-27B , IL27B , IL35B
UniProt: P29459, Q14213
Puffer: Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Expression System: E. coli
Formulierung: Lyophilized powder
Sequenz: N-terminal His-Tag, The IL35 complex composed of IL27B subunit (Arg21~Lys229 of NP_005746.2) and the mature form of human IL12A (Arg23~Ser219 of NP_000873.2) linked by a polypeptide linker (GGGGS)3
Anwendungsbeschreibung: IL35 (Interleukin 35) is an IL-12 family cytokine, which is a dimeric protein composed of IL-12alpha and IL-27beta chains. IL35 is thought to mediate the immune inhibitory function of regulatory T cells and has been proven to promotes pancreas cancer growth thr