Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through bi
Jaekel S. et. al. Importins fulfill a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. EMBO J. 21:377-386(2002).
Antibody Type:
Primary Antibody
Application Verdünnung:
WB: 1:500-1:2,000 ,FC: 1:50-1:100
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