Mitochondria-derived peptide MOTS-c, Mitochondrial open reading frame of the 12S rRNA-c
MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame (sORF) within the mitochondrial 12S rRNA. MOTS-c, which is a contraction of mitochondrial open reading frame of the 12S rRNA-c, regulates insulin sensitivity and metabolic homeostasi