SARS-CoV-2 S2 N defined peptide pool

Artikelnummer: MAB-3620-1
Artikelname: SARS-CoV-2 S2 N defined peptide pool
Artikelnummer: MAB-3620-1
Hersteller Artikelnummer: 3620-1
Alternativnummer: MAB-3620-1
Hersteller: MABTECH
Kategorie: Antikörper
Applikation: Cell stimulation
Spezies Reaktivität: Human
Alternative Synonym: COV2, COV-2, COVID-19, SARS-COV-2, SARS-COV, CORONA, NCOV, COVID, COVID19
The peptide pool is recommended for quantification of the number of cytokine secreting cells specific for SARS-CoV-2 S2 and N proteins. The peptide pool has been validated using human PBMC from COVID-19 convalescent individuals previously PCR-confirmed a

Peptide pool for stimulation of cells specific for SARS-CoV-2 S2 and N proteins.

The peptide pool is recommended for quantification of the number of cytokine secreting cells specific for SARS-CoV-2 S2 and N proteins. The peptide pool has been validated using human PBMC from COVID-19 convalescent individuals previously PCR-confirmed as SARS-CoV-2 positive.

The SARS-CoV-2 S2 N defined peptide pool contains 41 peptides from the human SARS-CoV-2 virus. The peptides are derived from the spike and nucleoprotein. The synthetic peptides are >95% pure.

HLA types covered by the SARS-CoV-2 S2 N defined peptide pool

The SARS-CoV-2 derived T-cell epitopes were defined with the help of T-cell assays or from positive MHC binding assays (Ahmed SF., et al.). Based on these assays this peptide pool covers the following MHC alleles: HLA-A*01:01, HLA-A*02:01, HLA-A*03:01, HLA-A*11:01, HLA-A*23:01, HLA-A*24:02, HLA-A*31:01, HLA-A*68:01, HLA-B*07:02, HLA-B*15:01, HLA-B*27:05, HLA-B*35:01, HLA-B*40, HLA-B*51:01, HLA-DRB1*01:01, and HLA-DRB1*04:01.