SARS-CoV-2 S2 N defined peptide pool
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Artikelname: | SARS-CoV-2 S2 N defined peptide pool |
Artikelnummer: | MAB-3620-1 |
Hersteller Artikelnummer: | 3620-1 |
Alternativnummer: | MAB-3620-1 |
Hersteller: | MABTECH |
Kategorie: | Antikörper |
Applikation: | Cell stimulation |
Spezies Reaktivität: | Human |
Alternative Synonym: | COV2, COV-2, COVID-19, SARS-COV-2, SARS-COV, CORONA, NCOV, COVID, COVID19 |
The peptide pool is recommended for quantification of the number of cytokine secreting cells specific for SARS-CoV-2 S2 and N proteins. The peptide pool has been validated using human PBMC from COVID-19 convalescent individuals previously PCR-confirmed a |
Peptide pool for stimulation of cells specific for SARS-CoV-2 S2 and N proteins.The peptide pool is recommended for quantification of the number of cytokine secreting cells specific for SARS-CoV-2 S2 and N proteins. The peptide pool has been validated using human PBMC from COVID-19 convalescent individuals previously PCR-confirmed as SARS-CoV-2 positive. The SARS-CoV-2 S2 N defined peptide pool contains 41 peptides from the human SARS-CoV-2 virus. The peptides are derived from the spike and nucleoprotein. The synthetic peptides are >95% pure. HLA types covered by the SARS-CoV-2 S2 N defined peptide poolThe SARS-CoV-2 derived T-cell epitopes were defined with the help of T-cell assays or from positive MHC binding assays (Ahmed SF., et al.). Based on these assays this peptide pool covers the following MHC alleles: HLA-A*01:01, HLA-A*02:01, HLA-A*03:01, HLA-A*11:01, HLA-A*23:01, HLA-A*24:02, HLA-A*31:01, HLA-A*68:01, HLA-B*07:02, HLA-B*15:01, HLA-B*27:05, HLA-B*35:01, HLA-B*40, HLA-B*51:01, HLA-DRB1*01:01, and HLA-DRB1*04:01.
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