TH-257 is a potent inhibitor of LIMK1 and LIMK2 with IC50 values of 84 nM and 39 nM for LIMK1 and LIMK2, respectively, and it can be used as a chemical probe for LIMK1 and LIMK2. TH-257 is an allosteric inhibitor targeting a binding pocket induced by an
Molekulargewicht:
422.54
Reinheit:
98.01
CAS Nummer:
[2244678-29-1]
Formel:
C24H26N2O3S
Target-Kategorie:
LIM Kinase (LIMK)
Anwendungsbeschreibung:
Reference compound
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