PIK-75 hydrochloride is a reversible DNA-PK and p110alpha-selective inhibitor, which inhibits DNA-PK, p110alpha and p110gamma with IC50s of 2, 5.8 and 76 nM, respectively. PIK-75 hydrochloride inhibits p110alpha >200-fold more potently than p110beta (IC50=1.3 µM)[1][2]. PI
Molekulargewicht:
488.74
Reinheit:
99.72
CAS Nummer:
[372196-77-5]
Formel:
C16H15BrClN5O4S
Target-Kategorie:
Apoptosis,DNA-PK,PI3K
Anwendungsbeschreibung:
Reference compound
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