PLX647 is an orally active, highly specific dual FMS and KIT kinase inhibitor, with IC50s of 28 and 16 nM, respectively. PLX647 shows selectivity for FMS and KIT over a panel of 400 kinases at a concentration of 1 µM except FLT3 and KDR (IC50s=91 and 130
Molekulargewicht:
382.38
Reinheit:
99.79
CAS Nummer:
[873786-09-5]
Formel:
C21H17F3N4
Target-Kategorie:
c-Fms,c-Kit
Anwendungsbeschreibung:
Reference compound
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