ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFbetaRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic pro
Molekulargewicht:
572.62
CAS Nummer:
[2489611-06-3]
Formel:
C29H35F3N6O3
Target-Kategorie:
TGF-beta Receptor
Anwendungsbeschreibung:
Reference compound
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