INCB13739 is an orally active, potent, selective and tissue-specific11beta-HSD1 (11beta-hydroxysteroid dehydrogenase 1) inhibitor, with IC50 values of 3.2 nM (11beta-HSD1 enzymatic) and 1.1 nM (11beta-HSD1 PBMC), respectively. INCB13739 can be used for type 2 diabet