PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor (IC50: 15 nM). PDE1-IN-5 has anti- inflammatory activity, and inhibits expression of iNOS, TNF-alpha, IL-1alpha, IL-1beta, and IL-6 induced by LPS. PDE1-IN-5 has anti-inflammatory bowel disease (IBD) effects i
Molekulargewicht:
444.54
CAS Nummer:
[2982945-34-4]
Formel:
C27H29FN4O
Target-Kategorie:
Phosphodiesterase (PDE)
Anwendungsbeschreibung:
Reference compound
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