EGFR/CDK2-IN-2 (compound 6a) is a dual inhibitor of EGFR and CDK-2 with IC50s of 19.6 and 87.9 nM, respectively. EGFR/CDK2-IN-2 induces apoptosis in MCF-7 cells and arrests the cell cycle in the S phase. EGFR/CDK2-IN-2 has significant anti-cancer cell to
Molekulargewicht:
884.99
Formel:
C49H32N12O2S2
Target-Kategorie:
CDK,EGFR
Anwendungsbeschreibung:
Reference compound
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