PARP1-IN-27 (Compound 9B) is the inhibitor for PARP1 and PARP2, with IC50 of 2.53 nM and 6.45 nM in cell SUM149PT. PARP1-IN-27 inhibits the proliferation of BRCA-mutated cancer cells SUM149PT, HCC1937 and Capan-1, with IC50 of 0.62, 1.91 and 4.26 µM resp
Molekulargewicht:
313.28
Formel:
C17H12FNO4
Target-Kategorie:
Apoptosis,PARP,Reactive Oxygen Species
Anwendungsbeschreibung:
Reference compound
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