P16INK4a Antibody, IgG2a, Clone: [CDKN2A/4499], Mouse, Monoclonal

Produktübersicht

• Artikelname: P16INK4a Antibody, IgG2a, Clone: [CDKN2A/4499], Mouse, Monoclonal
• Artikelnummer: NBT-1029-MSM3-P1ABX
• Hersteller Artikelnummer: 1029-MSM3-P1ABX
• Alternativnummer: NBT-1029-MSM3-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Purifiedrecombinantprokaryoticfull-lengthhumanp16INK4aprotein
• Alternative Synonym: CDK4 inhibitor p16 INK4, CDK4I, CDKN2A, Cell cycle negative regulator beta, CMM2, Cyclin dependent kinase 4 inhibitor A, Melanoma p16 inhibits CDK4, MLM, MTS1, Multiple tumor suppressor 1, p14, p16, p19, P19ARF, TP16

Produktbeschreibung

p16INK4a is a tumor suppressor protein. It is a specificinhibitor of cdk4/cdk6, and a tumorsuppressor involved inthe pathogenesis of a variety of malignancies. Recentanalyses of the p16INK4a gene revealed homozygousdeletions, nonsense, missense, or frame

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [CDKN2A/4499]
• Molekulargewicht: 14kDa
• Isotyp: IgG2a
• NCBI: 1029
• UniProt: P42771
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal diluti

Bilder

SDS-PAGE Analysis of Purified P16I