Recombinant IDH1-R132H (Isocitrate Dehydrogenase) Antibody, Clone: [IDH1/6806R], Rabbit, Monoclonal

Artikelnummer: NBT-3417-RBM6-P1ABX
Artikelname: Recombinant IDH1-R132H (Isocitrate Dehydrogenase) Antibody, Clone: [IDH1/6806R], Rabbit, Monoclonal
Artikelnummer: NBT-3417-RBM6-P1ABX
Hersteller Artikelnummer: 3417-RBM6-P1ABX
Alternativnummer: NBT-3417-RBM6-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant fragment of human IDH1 protein (around aa 281-414) (exact sequence is proprietary)
Alternative Synonym: Cytosolic NADP-isocitrate dehydrogenase, Epididymis luminal protein 216, Epididymis secretory protein Li 26, HEL-216, HEL-S-26, ICDH, IDCD, IDH1, IDP, IDPC, Isocitrate dehydrogenase 1 (NADP+) soluble, NADP dependent isocitrate dehydrogenase peroxisomal,
IDH1 R132H antibody binds to IDH1-mutated protein, but does not bind the wild-type IDH1 protein. IDH1 R132H point mutations are frequently seen in World Health Organization grade II and III gliomas and are believed to constitute an early step in tumorige
Klonalität: Monoclonal
Klon-Bezeichnung: [IDH1/6806R]
Molekulargewicht: 45-47kDa
NCBI: 3417
UniProt: O75874
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Recombinant Monoclonal Antibody
Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal diluti
FFPE prostate carcinoma with IDH1-R132H mutation stained with