MDM2 Antibody, IgG1, Clone: [SMP14], Mouse, Monoclonal

Produktübersicht

• Artikelname: MDM2 Antibody, IgG1, Clone: [SMP14], Mouse, Monoclonal
• Artikelnummer: NBT-4193-MSM1-P1
• Hersteller Artikelnummer: 4193-MSM1-P1
• Alternativnummer: NBT-4193-MSM1-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthetic peptide (aa 154-167) of human MDM2 protein.
• Alternative Synonym: ACTFS, Double minute 2 protein, E3 ubiquitin-protein ligase, Hdm2, HDMX, MDM2, MDM2 oncogene E3 ubiquitin protein ligase, MDM2BP, Mouse Double Minute 2, MTBP, Murine Double Minute Chromosome 2, p53 Binding Protein Mdm2, p53-binding protein Mdm2

Produktbeschreibung

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [SMP14]
• Molekulargewicht: ~90kDa
• Isotyp: IgG1
• NCBI: 4193
• UniProt: Q00987
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Western Blot Analysis of human HepG2 cell lysate using MDM2 Mouse Monoclonal Antibody (SMP14).

Formalin-fixed, paraffin-embedded human br