Recombinant MDM2 Antibody, Clone: [MDM2/7190R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant MDM2 Antibody, Clone: [MDM2/7190R], Rabbit, Monoclonal
• Artikelnummer: NBT-4193-RBM11-P0
• Hersteller Artikelnummer: 4193-RBM11-P0
• Alternativnummer: NBT-4193-RBM11-P0-20,NBT-4193-RBM11-P0-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant human MDM2 protein fragment (exact sequence is proprietary)
• Alternative Synonym: ACTFS, Double minute 2 protein, E3 ubiquitin-protein ligase, Hdm2, HDMX, MDM2, MDM2 oncogene E3 ubiquitin protein ligase, MDM2BP, Mouse Double Minute 2, MTBP, Murine Double Minute Chromosome 2, p53 Binding Protein Mdm2, p53-binding protein Mdm2

Produktbeschreibung

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MDM2/7190R]
• Molekulargewicht: ~90kDa
• NCBI: 4193
• UniProt: Q00987
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio