Recombinant MDM2 Antibody, Clone: [MDM2/7190R], Rabbit, Monoclonal

Artikelnummer: NBT-4193-RBM11-P1
Artikelname: Recombinant MDM2 Antibody, Clone: [MDM2/7190R], Rabbit, Monoclonal
Artikelnummer: NBT-4193-RBM11-P1
Hersteller Artikelnummer: 4193-RBM11-P1
Alternativnummer: NBT-4193-RBM11-P1-100
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant human MDM2 protein fragment (exact sequence is proprietary)
Alternative Synonym: ACTFS, Double minute 2 protein, E3 ubiquitin-protein ligase, Hdm2, HDMX, MDM2, MDM2 oncogene E3 ubiquitin protein ligase, MDM2BP, Mouse Double Minute 2, MTBP, Murine Double Minute Chromosome 2, p53 Binding Protein Mdm2, p53-binding protein Mdm2
MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive
Klonalität: Monoclonal
Klon-Bezeichnung: [MDM2/7190R]
Molekulargewicht: ~90kDa
NCBI: 4193
UniProt: Q00987
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.