MGMT (Marker of Suppressor of Mutation and Carcinogenesis) Antibody, IgG2, Clone: [MGMT/7454], Mouse, Monoclonal
Artikelnummer:
NBT-4255-MSM4-P0
Hersteller Artikelnummer:
4255-MSM4-P0
Alternativnummer:
NBT-4255-MSM4-P0-20
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Purified His-tagged MGMT protein
Alternative Synonym:
6 O methylguanine DNA methyltransferase, Methylated DNA protein cysteine methyltransferase, O 6 methylguanine DNA alkyltransferase, O 6 methylguanine DNA methyltransferase
Cancer chemotherapeutic alkylating agents (e.g. BCNU,) act by inducing formation of lethal cross links at the O6 alkylguanine position in DNA. MGMT transfers alkyl adducts from the O6 position of guanine in DNA (prior to cross link formation) to a c
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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