MGMT (Marker of Suppressor of Mutation and Carcinogenesis) Antibody, Clone: [MGMT/8186R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: MGMT (Marker of Suppressor of Mutation and Carcinogenesis) Antibody, Clone: [MGMT/8186R], Rabbit, Monoclonal
• Artikelnummer: NBT-4255-RBM8-P0
• Hersteller Artikelnummer: 4255-RBM8-P0
• Alternativnummer: NBT-4255-RBM8-P0-20,NBT-4255-RBM8-P0-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa1-100) of human MGMT (exact sequence is proprietary)
• Alternative Synonym: 6 O methylguanine DNA methyltransferase, Methylated DNA protein cysteine methyltransferase, O 6 methylguanine DNA alkyltransferase, O 6 methylguanine DNA methyltransferase

Produktbeschreibung

Cancer chemotherapeutic alkylating agents (e.g. BCNU,) act by inducing formation of lethal cross links at the O6 alkylguanine position in DNA. MGMT transfers alkyl adducts from the O6 position of guanine in DNA (prior to cross link formation) to a c

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MGMT/8186R]
• Molekulargewicht: 21.646 kDa
• NCBI: 4255
• UniProt: P16455
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio