8-Oxoguanine DNA Glycosylase Antibody, IgG2c, Clone: [CPTC-OGG1-1], Mouse, Monoclonal

Produktübersicht

• Artikelname: 8-Oxoguanine DNA Glycosylase Antibody, IgG2c, Clone: [CPTC-OGG1-1], Mouse, Monoclonal
• Artikelnummer: NBT-4968-MSM1-P1ABX
• Hersteller Artikelnummer: 4968-MSM1-P1ABX
• Alternativnummer: NBT-4968-MSM1-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human OGG1 protein
• Alternative Synonym: HMMH, HOGG1, MUTM, OGH1

Produktbeschreibung

8-oxoguanine (8-oxoG), an oxidized form of guanine, is produced by reactive oxygen species in both DNA and nucleotide pools during normal aging. Accumulation of 8-oxoG increases the occurrence of A:T to C:G or G:C to T:A transversionmutations, because 8-

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [CPTC-OGG1-1]
• Molekulargewicht: 39kDa
• Isotyp: IgG2c
• NCBI: 4968
• UniProt: O15527
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes), Optimal dilution for a