Mouse anti P53 (TP53 tumor suppressor protein), Clone: [DO-1], Monoclonal

Artikelnummer: NMB-MUB1501P
Artikelname: Mouse anti P53 (TP53 tumor suppressor protein), Clone: [DO-1], Monoclonal
Artikelnummer: NMB-MUB1501P
Hersteller Artikelnummer: MUB1501P
Alternativnummer: NMB-MUB1501P
Hersteller: NordicMubio
Wirt: Mouse
Kategorie: Antikörper
Applikation: ELISA, FC, ICC, IF, IHC-Fr, IHC-P, WB
Spezies Reaktivität: Human
P53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Alterations of the p53 tumor suppress
Klonalität: Monoclonal
Klon-Bezeichnung: [DO-1]
Isotyp: IgG2a kappa
UniProt: P04637
Puffer: Each vial contains 100ul 1mg/ml purified monoclonal antibody in phosphate buffered saline (PBS) containing 0.05% sodium azide. DO-1 recognizes a 53kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the w
Quelle: DO-1 is a mouse monoclonal IgG2a antibody derived by fusion of mouse myeloma Sp2/0-Ag14 cells with spleen cells from BALB/c mice immunized with recombinant human wild type p53 protein expressed in E. coli.
Anwendungsbeschreibung: The DO-1 antibody is suitable for the detection of p53 by Western blotting and detects a band of 53kDa in tumor tissue and cell extracts. The antibody is suitable for immunocytochemistry on permeabilized cells, and Immunohistochemistry on frozen and form