PCSK9 binds to the EGF-A domain of the LDLR and signals LDLR degradation. Reduced LDLR levels result in decreased LDL (low density lipid) metabolism leading to hypercholesterolemia. Additioanlly, PCSK9 may be implicated in the differentiation of cortical
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Reinheit:
Antigen Immunoaffiinity Purification
Formel:
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Anwendungsbeschreibung:
Antibody can be used for Western blotting (1:400 dilution) and immunocytochemistry (10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
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