Rabbit anti Human PH domain leucine-rich repeat-containing protein phosphatase 2

Produktübersicht

• Artikelname: Rabbit anti Human PH domain leucine-rich repeat-containing protein phosphatase 2
• Artikelnummer: NMB-X2737P
• Hersteller Artikelnummer: X2737P
• Alternativnummer: NMB-X2737P
• Hersteller: NordicMubio
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide derived from the human PHLPP2 protein
• Alternative Synonym: PHLPP2, PH domain leucine-rich repeat-containing protein phosphatase 2, PH domain leucine-rich repeat-containing protein phosphatase-like, PHLPP-like

Produktbeschreibung

PHLPP2 is a protein phosphatase that mediates dephosphorylation of Ser-473 of AKT1, Ser-660 of PRKCB isoform beta-II and Ser-657 of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function

Produkteigenschaften

• Konzentration: See vial for concentration
• Isotyp: Ig
• UniProt: Q6ZVD8
• Puffer: Provided as solution in phosphate buffered saline with 0.08% sodium azide
• Reinheit: Antigen Immunoaffinity Purification
• Formel: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Anwendungsbeschreibung

• Anwendungsbeschreibung: This antibody can be used for immunohistochemistry on formalin/paraffin sections (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions.