Rabbit anti Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking

Produktübersicht

• Artikelname: Rabbit anti Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking
• Artikelnummer: NMB-X2740P
• Hersteller Artikelnummer: X2740P
• Alternativnummer: NMB-X2740P
• Hersteller: NordicMubio
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide derived from the human PCSK9 protein reported to block PCSK9-LDLR interaction.
• Alternative Synonym: Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1

Produktbeschreibung

This anitbody is made to an epitope that is reported to block the PCSK9-LDLR (low density lipoprotein receptor) interaction. PCSK9 binds to the EGF-A domain of the LDLR and signals LDLR degradation. Reduced LDLR levels result in decreased LDL (low densit

Produkteigenschaften

• Konzentration: See vial for concentration
• Isotyp: IgG
• UniProt: Q8NBP7
• Puffer: Provided as solution in phosphate buffered saline with 0.08% sodium azide
• Reinheit: Antigen Immunoaffiinity Purification
• Formel: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Anwendungsbeschreibung

• Anwendungsbeschreibung: Antibody can be used for Western blotting (1:400 dilution) and immunocytochemisty (2 µg/ml). Optimal concentration should be evaluated by serial dilutions.