Synthetic peptide derived from human histone H2a.x protein. Sequence is unphosphorylated version of peptide used for Cat. No. X2752P
Alternative Synonym:
H2AFX, H2AX
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role