Keratin preparation from a human carcinoma was used as the immunogen for the CK8 antibody. The epitope of this mAb is located between amino acids 343-357.
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarci