VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and
Molekulargewicht:
415.49
CAS Nummer:
[1476074-39-1]
Formel:
C23H21D2N7O
Target-Kategorie:
DNA-PK
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