Talmapimod hydrochloride is a selective and ATP-competitive p38alpha inhibitor (IC50: 9 nM). It also shows about 10-fold selectivity over p38beta, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.
Molekulargewicht:
549.47
CAS Nummer:
[309915-12-6]
Formel:
C27H31Cl2FN4O3
Target-Kategorie:
p38 MAPK
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