UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting beta1i (LMP2), beta1c (LMP2), and beta5 (LMP2), with IC50s of 104 nM, 15 µM, and 1 µM, respectively. UK-101 exhibits a 144-fold and 10-fold higher affinity for beta1i than for the di
Molekulargewicht:
484.74
CAS Nummer:
[1000313-40-5]
Formel:
C25H48N2O5Si
Target-Kategorie:
Proteasome
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