PLX7683 is a paradox breaker. Paradox breakers overcame several known mechanisms of resistance to first-generation RAF inhibitors. Dissociating MAPK pathway inhibition from paradoxical activation might yield both improved safety and more durable efficacy
Molekulargewicht:
504.94
CAS Nummer:
[1652573-86-8]
Formel:
C23H19ClF2N4O3S
Target-Kategorie:
Others
T70308
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