SHP2/CDK4-IN-1 (compound 10) is a dual inhibitor targeting SHP2 and CDK4, exhibiting oral activity and high potency with IC50 values of 4.3 nM for SHP2 and 18.2 nM for CDK4. It effectively induces G0/G1 arrest, inhibiting the proliferation of TNBC cell l
Molekulargewicht:
693.21
CAS Nummer:
[2924036-87-1]
Formel:
C33H35ClF2N10OS
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