CZS-241 is an orally active, selective Polo-like Kinase (PLK) 4 inhibitor with an IC 50 of 2.6 nM that also inhibits TRKA at an IC 50 of 2.74 µM. It induces apoptosis and causes cell cycle arrest at the S/G2 phase, demonstrating potent antiproliferative
Molekulargewicht:
551.98
Formel:
C26H24ClF2N9O
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