ERD-3111 (Compound 44), an orally active PROTAC ERalpha degrader (DC50: 0.5 nM), exhibits efficacy in inhibiting tumor growth in both the parental MCF-7 xenograft model harboring wild-type ER and two ESR1-mutated mouse models. This compound has utility in th
Molekulargewicht:
854.89
CAS Nummer:
[2832865-25-3]
Formel:
C45H46F4N8O5
Target-Kategorie:
Estrogen Receptor/ERR
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