SARS-CoV-2-IN-60 (compound 5a) is a specific, irreversible inhibitor of SARS-CoV-2 nsp16-nsp10 methyltransferase, competing with S-adenosylmethionine (SAM) and exhibiting an IC50 of 9 µM and a Ki of 26 µM. It binds to a novel pocket near the SAM-binding
Molekulargewicht:
335.11
Formel:
C13H7Cl2F3N2O
Target-Kategorie:
SARS-CoV
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