IDH2R140Q-IN-2 is an orally active and potent IDH2R140Q inhibitor with an IC50 of 29 nM.IDH2R140Q-IN-2 possesses potential antitumour activity, reducing D2HG production in TF-1 cell lines carrying the IDH2R140Q mutation (IC50 of 10 nM) and inhibiting tum
Molekulargewicht:
484.4
CAS Nummer:
[2749568-16-7]
Formel:
C21H18F6N6O
Target-Kategorie:
Dehydrogenase
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