UMI-77

Artikelnummer: UBP-F7151
Artikelname: UMI-77
Artikelnummer: UBP-F7151
Hersteller Artikelnummer: F7151
Alternativnummer: UBP-F7151-25
Hersteller: UBPBio, LLC
Kategorie: Sonstiges
UMI-77 is a selective Mcl-1 inhibitor by binding of the BH3-binding groove of Mcl-1, by which it blocks the interactions of Bax/Mcl-1 and Bak/Mcl-1. UMI-77 inhibits growth of pancreatic cancer cells with IC50 of 3.4, 4.4, 12.5, 16.1, and 5.5 µM for BxPC-
Molekulargewicht: 468.34 g/mol
NCBI: 518303
Puffer: Powder, no buffer
Quelle: chemical synthesis