Serpin A1, Human, BioAssay(TM) DuoSet ELISA Development Kit (A1AT, alpha 1-Antitrypsin, alpha 1-Proteinase Inhibitor)

Artikelnummer: USB-145767
Artikelname: Serpin A1, Human, BioAssay(TM) DuoSet ELISA Development Kit (A1AT, alpha 1-Antitrypsin, alpha 1-Proteinase Inhibitor)
Artikelnummer: USB-145767
Hersteller Artikelnummer: 145767
Alternativnummer: USB-145767-1
Hersteller: US Biological
Kategorie: Kits/Assays
Applikation: ELISA
The human serpin superfamily consists of 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. Sample Type: Cell culture supernates Intended Use: This BioAssay(TM) DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human Serine Peptidase Inhibitor clade A member 1 (Serpin A1). DuoSets are designed for the analysis of cell culture supernates. Range: ~125-8000pg/ml Specificity: Recognizes natural and recombinant human Serine Peptidase Inhibitor clade A member 1 (Serpin A1). Kit Components: Goat anti-human Serpin A1 capture antibody, 1x vial Biotinylated goat anti-human Serpin A1 detection antibody, 1x vial Recombinant human Serpin A1 standard, 3x vials Streptavidin-HRP, 1x vial Storage and Stability: Store other components at 4C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.