GYPC, Recombinant, Human, aa1-57, His-Tag (Glycophorin-C Isoform 1, CD236, CD236R, GE, GPC, GPD, GYPD, PAS-2, PAS-2)

Produktübersicht

• Artikelname: GYPC, Recombinant, Human, aa1-57, His-Tag (Glycophorin-C Isoform 1, CD236, CD236R, GE, GPC, GPD, GYPD, PAS-2, PAS-2)
• Artikelnummer: USB-377831
• Hersteller Artikelnummer: 377831
• Alternativnummer: USB-377831-50
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

GYPC, also known as glycophorin-C isoform 1, is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. Source: Recombinant protein corresponding to aa1-57 from human GYPC, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~7.2kD (66aa), 18-28kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPMWSTRSP NSTAWPLSLE PDPGMASAST TMHTTTIAEP DPGMSGWPDG RMETSTPTIM HHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• Molekulargewicht: 7.2
• NCBI: 002092
• UniProt: P04921
• Reinheit: ~95% (SDS-PAGE)
• Formulierung: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.