KLK5, Recombinant, Human, aa67-293, His-Tag (Kallikrein-5, KLK-L2, KLKL2, SCTE)

Produktübersicht

• Artikelname: KLK5, Recombinant, Human, aa67-293, His-Tag (Kallikrein-5, KLK-L2, KLKL2, SCTE)
• Artikelnummer: USB-377878
• Hersteller Artikelnummer: 377878
• Alternativnummer: USB-377878-50,USB-377878-250
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

KLK5, also known as kallikrein-5, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. It is highly expressed in skin, mammary gland and testis. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14. Recombinant protein corresponding to aa67-293 from human KLK5, fused to His-Tag at C-terminal, expressed in insect cell (Baculovirus). Accession: NP_001070960 Molecular Weight: ~26.2kD (236aa) Amino Acid Sequence: ADLIINGSDC DMHTQPWQAA LLLRPNQLYC GAVLVHPQWL LTAAHCRKKV FRVRLGHYSL SPVYESGQQM FQGVKSIPHP GYSHPGHSND LMLIKLNRRI RPTKDVRPIN VSSHCPSAGT KCLVSGWGTT KSPQVHFPKV LQCLNISVLS QKRCEDAYPR QIDDTMFCAG DKAGRDSCQG DSGGPVVCNG SLQGLVSWGD YPCARPNRPG VYTNLCKFTK WIQETIQANS HHHHHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 26.2
• NCBI: 001070960
• UniProt: Q9Y337
• Reinheit: 95% (SDS-PAGE, reducing conditions). Endotoxin: 1EU/1ug (LAL)
• Formulierung: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.