Recombinant protein corresponding to aa338-487 from human E3 ubiquitin-protein ligase synoviolin protein.
Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) sy