Synthetic peptide corresponding to 13aa near the center of human TMPRSS2, located within aa320-370 of TMPRSS2. Species sequence homology: equine (100%), rabbit (100%), monkey (100%), sheep (100%)
TMPRSS2 is a plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth fac