Tozasertib, Free Base (N-[4-[[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanyl]phenyl]cyclopropanecarboxamide, VX-680, MK-0457, VX6), CAS [[639089-54-6]]

Produktübersicht

• Artikelname: Tozasertib, Free Base (N-[4-[[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanyl]phenyl]cyclopropanecarboxamide, VX-680, MK-0457, VX6), CAS [[639089-54-6]]
• Artikelnummer: USB-T8078
• Hersteller Artikelnummer: T8078
• Alternativnummer: USB-T8078-10,USB-T8078-25,USB-T8078-50,USB-T8078-100
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Tozasertib is a potent inhibitor of all aurora kinases, including the A, B and C isotypes (Ki=0.6nM, 18nM and 4.6nM, respectively). It also inhibits ABL kinase (Ki=30nM), an imatinib-resistant ABL mutant (T315I) kinase (Ki=42nM), and Flt-3 (Ki=30nM). Toz

Produkteigenschaften

• Molekulargewicht: 464.59
• Reinheit: ~99%
• Formulierung: Supplied as a white to off-white powder.
• CAS Nummer: [639089-54-6]