XIAP Associated Factor 1 (XAF1, X Chromosome linked Inhibitor of Apoptosis Associated Factor 1), Rabbit
Artikelnummer:
USB-X1034-05C
Hersteller Artikelnummer:
X1034-05C
Alternativnummer:
USB-X1034-05C-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Immunogen:
Synthetic peptide corresponding to amino acids at the C-terminus of human XAF-1 (Genbank accession CAA68030)
XAF-1 binds to XIAP, an inhibitor of caspases -3, -7, and -9, and triggers its relocation from the cytosol to the nucleus (1,2). Overexpression of XAF-1 results in the neutralization of XIAPs ability to inhibit cell death (1). XAF-1 is normally expressed