Synthetic peptide corresponding to aa283-301, QEKCRWLASSKGKQVRNFS to the C-terminus of human XIAP-associated factor 1.
XIAP-associated factor 1 (XAF1) binds to X-linked inhibitor of apoptosis (XIAP) and antagonizes the anticaspase activity of XIAP. XAF1 is expressed in all adult and fetal tissues but is frequently down-regulated in cancer cell lines. At least 7 isoforms