Small Molecules for SARS-CoV-2 research
We all hope for the early availability of validated compounds that can help in the fight against the coronavirus SARS-CoV-2. Research groups around the world are working to identify suitable therapy targets and the first promising compounds are already being tested in clinical trials. At BIOZOL you will find a broad portfolio of relevant biochemicals for the development of therapeutic approaches against COVID-19.
Validated modulators for the development of COVID-19 therapeutics
As of yet, there are no agents clinically validated to help stop the spread of the novel coronavirus SARS-CoV-2. Gordon et al. recently identified 332 SARS-CoV-2-human protein-protein interactions and 67 druggable human proteins as potential targets for developing therapeutics (note that this paper has not yet been subject to peer review). Focus Biomolecules offer a selection of according targets and validated small molecule modulators.
>> Relevant small molecules from Focus Biomolecules
Carbosynth has a portfolio of biochemicals available, which where published to interact with coronaviruses.
>> Biosynth Carbosynth's biochemicals with anti-coronaviral activity
Anti-COVID-19 Compound Library (CADD)
TargetMol developed a Anti-COVID-19 compound library (CADD). The unique collection of 362 compounds having the potential of anti-SARS-CoV-2 activity can be used for high throughput screening and high content screening. Targets include RBD, ACE2, Mpro（3CLpro, PLpro, nsp15, nsp16, PP1a X-domain, and RdRp (nsp12).
>> TargetMol's Anti-COVID-19 compound library (Art.-Nr. TGM-L1711)
Antiviral active plant lectins
Based on prior studies on coronaviruses such as SARS-CoV and MERS-CoV, mannose-specific plant lectins can be used to investigate antiviral properties of the novel coronavirus SARS-CoV-2, the virus that causes COVID-19.
Our partner Vector Laboratories is an established manufacturer of many plant lectins that are described in the literature as valuable tools in ongoing research to elucidate their potential in suppression of viral activity. Below is a list of mannose-specific and mannose/glucose-specific lectins, available in unconjugated and conjugated formats.