We would like to invite you to participate in our partner company GeneTex's upcoming webinar on extracellular vesicles as a tool for predicting response to cancer treatment.

Chondrex’s mission is to accelerate the rate of discovery in immunology research by providing scientists with high quality, reliable products. Chondrex provides Collagen Detection ELISA Kits for quantifying various species of type I and type II collagen, as well as total collagen detection.  

We would like to invite you to participate in our partner company MBL's upcoming live webinar on organoid cultures.   Webinar: Improve your organoid cultures with Wnt3a and FGF-Max Join Kazuya Arai, MS, Research leader, for a live webinar on Tuesday, November 15t...

Glial fibrillary acidic protein (GFAP) is a signature intermediate filament (IF) in astrocytes, that contributes to synapse formation and axonal metabolic homeostasis in the CNS. GFAP induction is crucial for the formation of extended and thickened astrocytic processes (astrocytosis) during neural repair. Chronic reactive astrocytosis is linked to several neuroinflammatory and neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. In 2018, the FDA authorized the first blood test to evaluate mild traumatic brain i...

Bio X Cell InVivoSIM™ non-therapeutic antibodies are research-grade biosimilar monoclonal antibodies that have the same active biological component as the original therapeutic antibodies. Biosimilars make it possible to study the biological effects of a drug without the need to source an expensive pharm...

We would like to invite you to participate in our partner company GeneTex's upcoming webinar on RAS genes in development and cancer. Webinar: RAS genes in development and cancer RAS genes have gained prominence due to their implication in human cancer. Mammals harbor three RAS loci (HRAS, NRA...

Inflammasomes are multiprotein complexes, responsible for the activation of inflammatory responses. Inflammasome activation is initiated by various cytosolic pattern recognition receptors (PRRs), including the NLR family of receptors. The NLRP3 inflammasome assembles NLRP3, ASC, and pro-caspase-1, leading to the activation of caspase-1, the cleavage and secretion of interleukin 1β (IL-1β) and interleukin 18 (IL-18) in response to diverse stimuli. NEK7 is the smallest of the eleven (NEK1-...

Immune checkpoints are regulators of the immune system which prevent the immune system from attacking self-antigens indiscriminately.  While this is critical to preventing auto-immune disease it also causes the immune system to be ineffective in eradicating or suppressing cancer. Tumor cells exploit certain immune-checkpoint pathways as a major mechanism of immune resistance, particularly against T cells that are specific for tumor antigens. Because many of these immune checkpoints are initiated by ligand-receptor interactions, they can...

PathPlus™ antibodies from LifeSpan  Biosciences (LSBio) represent the highest quality reagents available for research pathology applications. These reagents were selected from among thousands of antibodies, tested in immunohistochemistry on formalin...

DNA is a macromolecule capable of adopting many different conformations. In addition to the canonical Watson-Crick B-DNA, at least another 10 different conformations have been identified, with Z-DNA in particular attracting more and more attention (Wang et al., 2007). Z-DNA...