Gamma Proteins UK

High quality recombinant Fc receptors

Gamma Proteins was founded in the United Kingdom in 2023 with a vision to deliver substantially lower cost protein reagents to scientists worldwide without compromising on purity and biological activity. Specifically, Gamma Proteins is focussed on the supply of Fc gamma receptors and FcRn in bulk quantities to customers worldwide through a network of trusted distributors.

Manufacturing

All of Gamma Proteins recombinant proteins are manufactured in Human Embryonic Kidney (HEK) 293 cells. The use of mammalian cells ensures that the correct post-translational modifications, in particular glycosylation, are correctly incorporated to ensure full activity of the manufactured protein. Each batch of protein is produced from the exact same sequence, which is available to download on the respective product page, ensuring batch to batch reproducibility.

Quality

All recombinant proteins are purified to a purity level of at least 95% as determined by SDS-PAGE and SEC-HPLC to ensure the highest level of product purity. Biological activity is determined using surface plasmon resonance (SPR) on a Biacore instrument to measure the binding kinetics of the protein product to an appropriate ligand or receptor. SDS-PAGE, SEC-HPLC and SPR are performed on all batches of protein prior to release and batch specific product data can be found on the respective certificate of analysis (COA).

8 reasons to use Gamma Proteins

	Purity - Final product purity is determined by SEC-HPLC with a quality threshold >95% monomer purity.
	Activity - Biological activity of recombinant proteins is confirmed by Surface Plasmon Resonance.
	Mammalian expression - All recombinant proteins are produced in Human Embryonic Kidney 293 (HEK293) cells, ensuring correct folding and post-translational modification.
	Animal free - All proteins are manufactured in an animal component free platform with no carrier proteins added to the final products.
	Reproducibility - All proteins are produced recombinantly and quality & activity is confirmed for every batch.
	Low endotoxin - All products are prepared in an endotoxin free process to ensure they have < 1 EU / mg.
	Site-specific biotinylation - All products contain an AVI-tag for site-specific biotinylation ensuring greater reproducibility and preferential orientation for assays.
	Lyophilized - All products come lyophilized for longer stability and reduced environmental impact from transport.