LifeSpan Biosciences

Antibodies for IHC

LifeSpan Biosciences (LSBio) provides high quality antibodies for immunohistochemistry, including >500,000 monoclonal and polyclonal primary antibodies against most known targets proteins. They cover all major research species, applications, and are available in multiple conjugated forms. In addition to this extensive selection of antibodies, LSBio also offers two additional lines of products, the IHC-plus™ and PathPlus™ Antibody Line that offer highest preformance in Immunohistochemistry and best available evaluation for human pathology:

IHC-plus™ antibodies

LSBio's IHC-plus™ antibodies have been tested and identified as being optimal for use in immunohistochemistry (IHC) against formalin-fixed paraffin-embedded (FFPE) human tissues under LSBio's standardized IHC-plus™ immunohistochemistry protocol.

Each antibody is tested at multiple concentrations on more than 20 normal human tissue types, and when appropriate, multiple normal brain regions and/or cancer types. LSBio's IHC protocol has been developed over the past 15 years as the most optimal method of immunolabeling FFPE tissues, the most common fixation method used by pathology labs worldwide. A LifeSpan pathologist, with extensive experience evaluating IHC, analyzes the localization profile of each antibody, identifying positive and negative cell types, signal strength, subcellular and extracellular staining, and staining artifacts. This information is then compared with all published expression and localization data available for the protein. This enables LSBio to evaluate how each antibody behaves in IHC, including its specificity to the target protein, its sensitivity of detection, and any non-specific staining characteristics that it may display. In order to be selected as an IHC-plus™ brand antibody, antibodies must have a close correlation to the published literature, be high affinity, display minimal staining artifacts, and have a high signal-to-noise ratio, such that its specific staining is considerably higher than its level of nonspecific background staining.

PathPlus™ antibodies

The LSBio PathPlus™ antibodies represent the highest quality reagents available for research pathology applications. This series of reagents was selected from among thousands of antibodies that were tested in immunohistochemistry on formalin-fixed paraffin-embedded (FFPE) tissues to be the best performers. Each antibody has been tested on 21 human tissues, including specialized tissues such as cancers or brain regions, compared to up to 20 different antibodies to that target, and ranked by performance. The antibodies that showed the highest specificity and least nonspecific staining on formalin-fixed paraffin-embedded tissues are now available for your research, designated by the PathPlus™ brand.

Whether investigating cancer biomarkers, neurodegenerative diseases, apoptotic pathways or lymphocyte subsets in immune disorders, the LSBio PathPlus™ antibodies are guaranteed to work in IHC for research pathology applications.

LifeSpan Biosciences Antibodies:

more than 500,000 primary antibodies for many species and applications like immunoblotting, IHC, immunofluorescence and cell sorting
more than 25,000 IHC-plus™ antibodies: intensively tested on formalin-fixed paraffin sections, with 100% satisfaction guarantee
more than 2.000 PathPlus™ antibodies that are even more intensely evaluated for pathology in three categoryies: Cancer Pathology, Cancer, Neuroscience
polyclonal rabbit antibodies
secondary antibodies